Prevelle Silk Injections – Benefits, Cost & Side Effects

Reviewed by Mitchel Goldman, MD

Prevelle Silk is a soft tissue filler that is injected into facial skin to reduce moderate to severe wrinkles such as nasolabial folds (those ridges that may span from the root of the nose to the angle of the mouth). It was approved in March 2008 by the Food and Drug Administration.

What Is Prevelle Silk, and How Does It Work?

A soft, colorless gel, Prevelle Silk is a hyaluronic acid soft tissue filler that contains the local anesthetic lidocaine. The main advantage of this filler is that injections are less painful than other hyaluronic acid products that don't contain lidocaine.

Hyaluronic acid is a chief component of connective tissues, and it adds volume and fullness to the skin. The number of Prevelle Silk injections that a person receives depends on how deep the fold is.  Some people require a full syringe and others will need one or two syringes. Each doctor has a different technique for injections. Prevelle Silk results last for three to four months.

Prevelle Silk Side Effects

Side effects of Prevelle Silk tend to be mild to moderate and last seven days or less. The most common ones include temporary injection site reactions such as swelling, pain/tenderness, redness and lumps/bumps.

Cost of Prevelle Silk

Prevelle Silk costs about $400 for a .075 milliliters (mL) syringe. Sometimes more than one syringe is necessary, depending on the size and scope of the area to be treated.

If the cost of Prevelle Silk is more than you can pay all at once, ask your doctor about payment plan options. For financing options and tips, please read the article about patient financing.

About the Reviewer of This Article

Mitchel P. Goldman, MD, is certified by the American Board of Dermatology and a Fellow of the American Society for Dermatologic Surgery, American Society of Laser Medicine and Surgery and the American Academy of Cosmetic Surgery. His practice focuses on injectable fillers and Botox, phlebology (the study of veins), laser surgery and liposuction. Dr. Goldman received his medical degree from Stanford University School of Medicine and dermatology specialty training at the University of California, Los Angeles. He maintains hospital staff privileges at Scripps Hospital and the VA Medical Center, both in La Jolla, California, where he practices, and is a volunteer clinical professor of dermatology/medicine at the University of California, San Diego. He is an associate editor of Dermatologic Surgery and The Journal of Cosmetic Dermatology and has authored more than 300 medical articles and 21 medical textbooks on cosmetic surgery.

[page updated October 2008]